| medicine | /r/medicine: a subreddit for medical professionals | 509,213 |
| Psychonaut | Psychonaut | 500,805 |
| GymMotivation | Gym Motivation | 491,428 |
| WeightLossAdvice | WeightLossAdvice | 477,308 |
| gainit | STOP Drinking Olive Oil! | 466,109 |
| autism | Autism | 444,138 |
| Supplements | Supplements | 413,337 |
| naturalbodybuilding | Natural (No Juice) BodyBuilding Discussion | 404,638 |
| MedicalGore | Medical Gore | 402,853 |
| PHitness | Philippine Fitness | 398,830 |
| weightroom | A subreddit for general treadmill enthusiasm | 392,103 |
| fatlogic | fatlogic | 389,963 |
| workout | Workout: in fitness we are one | 386,480 |
| Biohackers | Biohackers | 357,730 |
| CPTSD | A support community for those affected by C-PTSD | 338,241 |
